| lewis | (n) United States rock star singer and pianist (born in 1935), Syn. Jerry Lee Lewis |
| lewis | (n) United States athlete who won gold medals at the Olympics for his skill in sprinting and jumping (born in 1961), Syn. Frederick Carleton Lewis, Carl Lewis |
| lewis | (n) United States explorer and soldier who lead led an expedition from St. Louis to the mouth of the Columbia River (1774-1809), Syn. Meriwether Lewis |
| lewis | (n) United States labor leader who was president of the United Mine Workers of America from 1920 to 1960 and president of the Congress of Industrial Organizations from 1935 to 1940 (1880-1969), Syn. John L. Lewis, John Llewelly Lewis |
| lewis | (n) United States novelist who satirized middle-class America in his novel Main Street (1885-1951), Syn. Sinclair Lewis, Harry Sinclair Lewis |
| lewis | (n) English critic and novelist; author of theological works and of books for children (1898-1963), Syn. Clive Staples Lewis, C. S. Lewis |
| lewis and clark expedition | (n) an expedition sent by Thomas Jefferson to explore the northwestern territories of the United States; led by Meriwether Lewis and William Clark; traveled from St. Louis to the mouth of the Columbia River from 1803 to 1806 |
| lewisia | (n) genus of western North American low-growing herbs having linear woolly leaves and large pink flowers, Syn. genus Lewisia |
| lewiston | (n) a town in southwestern Maine to the north of Portland |
| lewiston | (n) a town in northwestern Idaho |
