n. 1. [ Cf. Sachem. ] The head of a tribe among the American Indians; a chief; -- generally used as synonymous with sachem, but some writters distinguished between them, making the sachem a chief of the first rank, and a sagamore one of the second rank. “Be it sagamore, sachem, or powwow.” Longfellow. [ 1913 Webster ]

2. A juice used in medicine. [ Obs. ] Johnson. [ 1913 Webster ]